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Index > Protein center > Casq1(Gene name) > Mouse
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  • Casq1 (Gene name),
  • Calsequestrin-1 (Protein name ),  CASQ1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Casq1;
    Protein name:
    Calsequestrin-1;
    Alternative:
    Calsequestrin, skeletal muscle isoform;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
    Subcellular Location:
    Sarcoplasmic reticulum lumen This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells.
    Protein Attributes:
    Sequence length:
    405
    Sequence:
    50:
    MRATDRMGAR | AVSELRLALL | FVLVLGTPRL | GVQGEDGLDF | PEYDGVDRVI | 
    100:
    NVNAKNYKNV | FKKYEVLALL | YHEPPEDDKA | SQRQFEMEEL | ILELAAQVLE | 
    150:
    DKGVGFGLVD | SEKDAAVAKK | LGLTEEDSVY | VFKGDEVIEY | DGEFSADTLV | 
    200:
    EFLLDVLEDP | VELIEGEREL | QAFENIEDEI | KLIGYFKSKD | SEHYKAYEDA | 
    250:
    AEEFHPYIPF | FATFDSKVAK | KLTLKLNEID | FYEAFMEEPM | TIPDKPNSEE | 
    300:
    EIVSFVEEHR | RSTLRKLKPE | SMYETWEDDL | DGIHIVAFAE | EADPDGYEFL | 
    350:
    ETLKAVAQDN | TENPDLSIIW | IDPDDFPLLV | PYWEKTFDID | LSAPQIGVVN | 
    400:
    VTDADSIWME | MDNEEDLPSA | DELEDWLEDV | LEGEINTEDD | DDDDDDDDDD | 
    405:
    DDDDD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Calsequestrin-1
    Cat.:
    E15017h
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    ELISA Kit for Mouse Calsequestrin-1
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    E15017m
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    Packing:
    96T
    ELISA Kit for Mouse Calsequestrin-1
    Cat.:
    E15017r
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    96T
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    ELISA Kit for Mouse Calsequestrin-1
    Cat.:
    E15017d
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Calsequestrin-1
    MSDS:
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    CLIA Kit for Mouse Calsequestrin-1
    Cat.:
    U15017r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Calsequestrin-1
    Cat.:
    U15017m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calsequestrin-1
    Cat.:
    U15017h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calsequestrin-1
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Calsequestrin-1
    Cat.:
    U15017d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Calsequestrin-1
    Cat.:
    P15017Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calsequestrin-1
    Polyclonal Antibody for Mouse Calsequestrin-1
    Polyclonal Antibody for Mouse Calsequestrin-1
    Cat.:
    P15017Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calsequestrin-1
    Cat.:
    P15017Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Calsequestrin-1
    Monoclonal Antibody for Mouse Calsequestrin-1
    Monoclonal Antibody for Mouse Calsequestrin-1
    Monoclonal Antibody for Mouse Calsequestrin-1
    Monoclonal Antibody for Mouse Calsequestrin-1
    Protein for Mouse Calsequestrin-1
    Protein for Mouse Calsequestrin-1
    Protein for Mouse Calsequestrin-1
    Protein for Mouse Calsequestrin-1
    Protein for Mouse Calsequestrin-1

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    References
    1. 1.
      "Cloning of the genes encoding mouse cardiac and skeletal calsequestrins: expression pattern during embryogenesis."
      Park K.-W. , Goo J.H. , Chung H.-S. , Kim H. , Kim D.-H. , Park W.-J.
      Gene217:25-30(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "Molecular cloning of human calmitine, a mitochondrial calcium binding protein, reveals identity with calsequestrine."
      Bataille N. , Schmitt N. , Aumercier-Maes P. , Ollivier B. , Lucas-Heron B. , Lestienne P.
      Biochem. Biophys. Res. Commun.203:1477-1482(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-47;SUBCELLULAR LOCATION;FUNCTION;TISSUE SPECIFICITY
      tissue: Skeletal muscle.
    4. 4.
      "Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1."
      Paolini C. , Quarta M. , Nori A. , Boncompagni S. , Canato M. , Volpe P. , Allen P.D. , Reggiani C. , Protasi F.
      J. Physiol. (Lond.)583:767-784(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;TISSUE SPECIFICITY
    5. 5.
      "Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice."
      Tomasi M. , Canato M. , Paolini C. , Dainese M. , Reggiani C. , Volpe P. , Protasi F. , Nori A.
      Am. J. Physiol.302:C575-C586(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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